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Research Associate – Assay Development

Location: South San Francisco, CA

Company Description:

Ambys Medicines is a biotechnology company focused on discovering and developing regenerative and restorative therapies for people with advanced liver disease. Founded by world-renowned experts in liver disease and regenerative medicine, Ambys is pioneering the application of novel modalities including cell and gene therapy, and gain-of-function drug therapy, to meet the urgent need for treatments that have the potential to restore liver function and prevent the progression to liver failure across multiple liver diseases that are untreatable or poorly treated today. Ambys was launched in 2018 by Third Rock Ventures and Takeda Pharmaceuticals with $140M in starting capital and is headquartered in South San Francisco, Calif.

Position Summary:

We are seeking a highly motivated in vitro assay development research associate with bioanalytical assay experience required to advance our understanding of biological processes underlying the development of a variety of liver diseases.  This individual will join a dynamic and growing multidisciplinary team focused on early stages of  small molecule lead discovery via development of in vitro biochemical/ biophysical and cell-based assays. A key component of the position will be to provide regular, high quality assay results to other team members and troubleshoot and develop approaches to optimize experimental procedures. The candidate will be flexible enough to work across projects supporting the many goals of the company. The successful candidate will work with direct supervision of a Scientist but show strong independence and a willingness to advance within a quickly growing company.

The successful candidate will be a decisive and results-oriented individual who is flexible, team-oriented, creative and able to excel in a multi-project, fast-track environment. If you thrive in a culture of collaboration and have an entrepreneurial spirit, we’d like to meet you.

Job Requirements:

  • B.S. or M.S. in a biological science discipline
  • At least 2 years relevant experience working at the bench in a biological sciences laboratory
  • The ability to plan and troubleshoot problems arising in biochemical assay development/screening is required
  • Execution of existing protocols and familiarity with proper documentation and communication of results from laboratory work
  • Experience in performing some of the following molecular/ biochemical/ immunochemical assays required- flow cytometry, qPCR, SDS-PAGE, ELISA and Western blotting
  • Experience with primary and ex-vivo cell culture models is desirable
  • Experience working with suspension and adherent mammalian cells is required
  • Experience with transfection of siRNA, shRNA and/or CRISPRs or lentiviral transduction delivery desirable
  • Experience with common laboratory software (SoftmaxPro, GraphPad Prism, Microsoft Office Suite, etc.)
  • Familiarity with ELN software preferred
  • Must be willing to work with ex-vivo preclinical samples (tissues, organs, biopsies) and possibly blood samples (whole blood and blood components)

If you would like to be considered for an opportunity at Ambys Medicines, please submit your CV with the title of the position in the subject line to

The well-being of our employees and their families is important to us. We offer comprehensive and competitive health, financial, paid time off and many other benefits designed to promote the health and financial well-being of our employees and their families.

Note to Recruitment Agencies: Please do not forward any agency resumes. Ambys Medicines is not responsible for any fees related to resumes that are unsolicited.

Ambys Medicines is an equal opportunity employer.